Several key issues emerged as pivotal in ongoing efforts to reform TSCA. Progress on these complex issues is central to the success of TSCA reform. To foster further discussion of these critical topics, ELI convened a series of issue-specific lunchtime webinars during the summer and fall of 2011 that provided a forum for focused dialogue among key players. On September 20, 2011, ELI convened the third panel in this series to explore reform of TSCA requirements and procedures for developing and reporting data on chemical hazards, use, and exposure. Topics included the scope of EPA authority to require information and data, including on new chemicals, such as nanomaterials; testing, including mutual acceptance of data and emerging methodologies; and the role of downstream users of chemicals.